Reaction: (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA)
- in pathway: Pyrimidine salvage
Cytosolic cytidine deaminase catalyzes the hydrolysis of cytidine or dexoycytidine to form uridine or deoxyuridine and ammonia (Laliberte and Momparler 1994). The active form of the enzyme is a tetramer (Chung et al. 2005).
Reaction - small molecule participants:
NH4+ [cytosol]
H2O [cytosol]
Reactome.org reaction link: R-HSA-73608
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Reaction input - small molecules:
water
Reaction output - small molecules:
ammonium
Reactome.org link: R-HSA-73608