Reaction: beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2
- in pathway: Pyrimidine catabolism
Cytosolic UPB1 (beta-ureidopropionase) catalyzes the reaction of 3-ureidoisobutyrate and H2O to form (R)-3-aminoisobutyrate, CO2, and NH3 (Tamaki et al. 2000; van Kuilenburg et al. 2004).
Reaction - small molecule participants:
CO2 [cytosol]
3AIB [cytosol]
NH4+ [cytosol]
H2O [cytosol]
H+ [cytosol]
UIBA [cytosol]
Reactome.org reaction link: R-HSA-73620
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Reaction input - small molecules:
water
hydron
3-ureidoisobutyrate(1-)
Reaction output - small molecules:
carbon dioxide
(R)-3-aminoisobutyric acid zwitterion
ammonium
Reactome.org link: R-HSA-73620