Reaction: SLC35A3 exchanges UDP-GlcNAc for UMP
- in pathway: Transport of nucleotide sugars
The human gene SLC35A3 encodes a UDP-GlcNAc transporter (Ishida et al. 1999). It is ubiquitously expressed and resides on the Golgi membrane where it transports UDP- N-acetylglucosamine (GlcNAc) into the Golgi lumen in exchange for UMP.
Reaction - small molecule participants:
UDP-GlcNAc [Golgi lumen]
UMP [cytosol]
UMP [Golgi lumen]
UDP-GlcNAc [cytosol]
Reactome.org reaction link: R-HSA-741450
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Reaction input - small molecules:
uridine 5'-monophosphate(2-)
UDP-N-acetyl-alpha-D-glucosamine(2-)
Reaction output - small molecules:
UDP-N-acetyl-alpha-D-glucosamine(2-)
uridine 5'-monophosphate(2-)
Reactome.org link: R-HSA-741450