Reaction: APRT catalyzes the conversion of adenine to AMP
- in pathway: Purine salvage
Cytosolic APRT dimer catalyzes the reaction of adenine and 5-phospho-alpha-D-ribose 1-diphosphate to form AMP and pyrophosphate (Holden et al. 1979; Silva et al. 2008).
Reaction - small molecule participants:
PPi [cytosol]
AMP [cytosol]
PRPP [cytosol]
Ade [cytosol]
Reactome.org reaction link: R-HSA-74213
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Reaction input - small molecules:
5-O-phosphonato-alpha-D-ribofuranosyl diphosphate(5-)
adenine
Reaction output - small molecules:
diphosphate(3-)
adenosine 5'-monophosphate(2-)
Reactome.org link: R-HSA-74213