Reaction: uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP]
- in pathway: Pyrimidine salvage
Cytosolic uridine phosphorylase (isoforms UPP1 and UPP2) catalyzes the reversible reactions of uracil with ribose 1-phosphate or deoxyribose 1-phosphate to yield uridine or deoxyuridine and orthophosphate (Watanabe and Uchida 1995; Johansson, 2003). The active form of UPP1 is a dimer (Rooslid et al. 2009).
Reaction - small molecule participants:
Pi [cytosol]
Ura [cytosol]
Reactome.org reaction link: R-HSA-74372
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Reaction input - small molecules:
uracil
Reaction output - small molecules:
hydrogenphosphate
Reactome.org link: R-HSA-74372