Reaction: (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP)

- in pathway: Pyrimidine catabolism
Cytosolic uridine phosphorylase (isoforms UPP1 and UPP2) catalyzes the reversible reactions of uridine or deoxyuridine with orthophosphate to yield uracil and ribose 1-phosphate or deoxyribose 1-phosphate (Watanabe and Uchida 1995; Johansson, 2003). The active form of UPP1 is a dimer (Rooslid et al. 2009).
Reaction - small molecule participants:
Ura [cytosol]
Pi [cytosol]
Reactome.org reaction link: R-HSA-74376

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Reaction input - small molecules:
hydrogenphosphate
ChEBI:43474
Reaction output - small molecules:
uracil
ChEBI:17568
Reactome.org link: R-HSA-74376