Reaction: Dephosphorylation of p-Y-IRS1,p-Y-IRS2

- in pathway: Signal attenuation
At the beginning of this reaction, 1 molecule of 'phospho-IRS' is present. At the end of this reaction, 1 molecule of 'Orthophosphate', and 1 molecule of 'IRS' are present.

This reaction takes place in the 'cytosol' and is mediated by the 'protein tyrosine phosphatase activity' of 'protein tyrosine phosphatase' (Pederson et al.2001).
Reaction - small molecule participants:
Pi [cytosol]
Reactome.org reaction link: R-HSA-74747

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Reaction input - small molecules:
Reaction output - small molecules:
hydrogenphosphate
ChEBI:43474
Reactome.org link: R-HSA-74747