Reaction: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1]
- in pathway: Triglyceride biosynthesis
Tetrameric diacylglycerol O-acyltransferase 1 (DGAT1) associated with the endoplasmic reticulum membrane catalyzes the reaction of 1,2-diacyl-glycerol and acyl-CoA to form triacylglycerol + CoASH (Cheng et al. 2001).
Reaction - small molecule participants:
TAG [cytosol]
CoA-SH [cytosol]
FACoA [cytosol]
DAG [cytosol]
Reactome.org reaction link: R-HSA-75900
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Reaction input - small molecules:
fatty acyl-CoA(4-)
1,2-diacyl-sn-glycerol
Reaction output - small molecules:
triglyceride
coenzyme A(4-)
Reactome.org link: R-HSA-75900