Reaction: Ethylene is oxidized to Ethylene oxide by CYP1A1
- in pathway: Xenobiotics
A simple example of epoxidation is the oxidation of an alkene (olefin) to the epoxide (oxirane), catalysed by CYP1A1. Even the simplest of epoxides (ethylene oxide) can react with DNA and amino groups in a protein.
Reaction - small molecule participants:
H2O [endoplasmic reticulum lumen]
NADP+ [endoplasmic reticulum lumen]
EtO [endoplasmic reticulum lumen]
O2 [endoplasmic reticulum lumen]
H+ [endoplasmic reticulum lumen]
C2H4 [endoplasmic reticulum lumen]
NADPH [endoplasmic reticulum lumen]
Reactome.org reaction link: R-HSA-76472
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Reaction input - small molecules:
dioxygen
hydron
ethene
NADPH
Reaction output - small molecules:
water
NADP(+)
oxirane
Reactome.org link: R-HSA-76472