Reaction: (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H
- in pathway: Beta oxidation of butanoyl-CoA to acetyl-CoA
At the beginning of this reaction, 1 molecule of 'NAD+', and 1 molecule of '(S)-3-Hydroxybutanoyl-CoA' are present. At the end of this reaction, 1 molecule of 'acetoacetyl-CoA', 1 molecule of 'H+', and 1 molecule of 'NADH' are present.
This reaction takes place in the 'mitochondrial matrix' and is mediated by the '3-hydroxyacyl-CoA dehydrogenase activity' of 'short chain 3-hydroxyacyl-CoA dehydrogenase homodimer'.
This reaction takes place in the 'mitochondrial matrix' and is mediated by the '3-hydroxyacyl-CoA dehydrogenase activity' of 'short chain 3-hydroxyacyl-CoA dehydrogenase homodimer'.
Reaction - small molecule participants:
ACA-CoA [mitochondrial matrix]
H+ [mitochondrial matrix]
NADH [mitochondrial matrix]
NAD+ [mitochondrial matrix]
3HB-CoA [mitochondrial matrix]
Reactome.org reaction link: R-HSA-77312
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Reaction input - small molecules:
NAD(1-)
(S)-3-hydroxybutanoyl-CoA
Reaction output - small molecules:
acetoacetyl-CoA(4-)
hydron
NADH(2-)
Reactome.org link: R-HSA-77312