Reaction: Deamination at C6 position of adenosine in Editosome (ADAR2)
- in pathway: C6 deamination of adenosine
At the beginning of this reaction, 1 molecule of 'H2O', and 1 molecule of 'Editosome (ADAR2) complex' are present. At the end of this reaction, 1 molecule of 'NH3', and 1 molecule of 'A to I edited RNA:Editosome (ADAR2) complex' are present.
This reaction takes place in the 'nucleus' and is mediated by the 'double-stranded RNA adenosine deaminase activity' of 'ADAR2 homodimer' (Zheng et al.2017).
This reaction takes place in the 'nucleus' and is mediated by the 'double-stranded RNA adenosine deaminase activity' of 'ADAR2 homodimer' (Zheng et al.2017).
Reaction - small molecule participants:
NH3 [nucleoplasm]
H2O [nucleoplasm]
Reactome.org reaction link: R-HSA-77615
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Reaction input - small molecules:
water
Reaction output - small molecules:
ammonia
Reactome.org link: R-HSA-77615