Reaction: PNPLA5 hydrolyzes TAG
- in pathway: Triglyceride catabolism
PNPLA5 (patatin-like phospholipase domain-containing protein 5, also known as GS2 like) catalyzes the hydrolysis of TAG (triacylglycerol) to DAG (diacylglycerol) and one molecule of LCFA (long chain fatty acid) (Gao and Simon 2007).
Reaction - small molecule participants:
LCFA(-) [cytosol]
DAG [cytosol]
H2O [cytosol]
TAG [cytosol]
Reactome.org reaction link: R-HSA-8848339
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Reaction input - small molecules:
water
triglyceride
Reaction output - small molecules:
long-chain fatty acid anion
1,2-diacyl-sn-glycerol
Reactome.org link: R-HSA-8848339