Reaction: NTPDase3 hydrolyzes nucleoside diphosphates
- in pathway: Phosphate bond hydrolysis by NTPDase proteins
NTPDase3 (CD39L3), encoded by the ENTPD3 gene, is a plasma membrane-bound ectonucleotidase that hydrolyzes extracellular NDPs to corresponding NMPs (Smith and Kirley 1998, Lavoie et al. 2004, Vorhoff et al. 2005, Kukulski et al. 2005).
Reaction - small molecule participants:
H+ [extracellular region]
Pi [extracellular region]
NMP [extracellular region]
H2O [extracellular region]
NDP [extracellular region]
Reactome.org reaction link: R-HSA-8851129
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Reaction input - small molecules:
water
nucleoside 5'-diphosphate(3-)
Reaction output - small molecules:
hydron
hydrogenphosphate
nucleoside 5'-monophosphate(2-)
Reactome.org link: R-HSA-8851129