Reaction: NTPDase8 hydrolyzes nucleoside diphosphates
- in pathway: Phosphate bond hydrolysis by NTPDase proteins
NTPDase8, encoded by the ENTPD8 gene, is the main liver ectonucleotide phosphatase. NTPDase8 belongs to the E-NTPDase family of nucleotide phosphatases and can hydrolyze NDPs to corresponding NMPs (Sévigny et al. 2000, Bigonnesse et al. 2004, Fausther et al. 2007).
Reaction - small molecule participants:
H+ [extracellular region]
Pi [extracellular region]
H2O [extracellular region]
Reactome.org reaction link: R-HSA-8851550
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Reaction input - small molecules:
water
Reaction output - small molecules:
hydron
hydrogenphosphate
Reactome.org link: R-HSA-8851550