Reaction: ADBRK1,2 phosphorylate AVPR2
- in pathway: Cargo recognition for clathrin-mediated endocytosis
AVPR2 is phosphorylated by ADBRK1 and 2 in an agonist-dependent manner as a prerequisite for beta-arrestin binding and endocytosis (Ren et al, 2005; reviewed in Gurevich and Gurevich, 2006).
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-8866268
======
Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-8866268