Reaction: pre-VLDL binds lipids to form VLDL
- in pathway: VLDL assembly
The assembly of very low-density lipoprotein (VLDL) occurs in two steps (Olofsson et al. 2000). In the second step, pre-VLDL in the smooth ER lumen binds the major lipids that form bona fide VLDL; triacylglycerols (TAG) (50%), phospholipids (PL) (20%), cholesterol (CHOL) (10%) and cholesteryl esters (CHEST) (5%).
Reaction - small molecule participants:
CHEST [smooth endoplasmic reticulum]
CHOL [smooth endoplasmic reticulum]
TAG [smooth endoplasmic reticulum]
PL [smooth endoplasmic reticulum]
Reactome.org reaction link: R-HSA-8866304
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Reaction input - small molecules:
cholesteryl ester
cholesterol
triglyceride
phospholipid
Reaction output - small molecules:
Reactome.org link: R-HSA-8866304