Reaction: SLC22A13 transports NCA from extracellular region to cytosol
- in pathway: Nicotinamide salvaging
Plasma membrane-associated SLC22A13 (solute carrier family 22 member 13, also known as OCTL3 - organic cation transporter-like 3) mediates the uptake of extracellular nicotinate (NCA). The protein is especially abundant in the kidney but is widely expressed in tissues of the body (Bahn et al. 2008).
Reaction - small molecule participants:
NCA [cytosol]
NCA [extracellular region]
Reactome.org reaction link: R-HSA-8869603
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Reaction input - small molecules:
nicotinate
Reaction output - small molecules:
nicotinic acid
Reactome.org link: R-HSA-8869603