Reaction: BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose
- in pathway: Nicotinate metabolism
BST1 dimer associated with the plasma membrane catalyzes the hydrolysis of extracellular NAD+ to yield NAM and ADP-ribose (Yamamoto-Katayama et al. 2002).
Reaction - small molecule participants:
H+ [extracellular region]
ADP-ribose [extracellular region]
NAM [extracellular region]
NAD+ [extracellular region]
H2O [extracellular region]
Reactome.org reaction link: R-HSA-8870346
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Reaction input - small molecules:
NAD(1-)
water
Reaction output - small molecules:
hydron
ADP-D-ribose(2-)
nicotinamide
Reactome.org link: R-HSA-8870346