Reaction: USP8 deubiquitinates LRIG1
- in pathway: Negative regulation of MET activity
The ubiquitin hydrolase USP8 can deubiquitinate LRIG1, thus interfering with LRIG1-mediated MET downregulation (Oh et al. 2014).
Reaction - small molecule participants:
H2O [cytosol]
Reactome.org reaction link: R-HSA-8875443
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Reaction input - small molecules:
water
Reaction output - small molecules:
Reactome.org link: R-HSA-8875443