Reaction: SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol
- in pathway: Cellular hexose transport
The sodium/glucose cotransporter 5 (SLC5A10, sodium glucose cotransporter 5, SGLT5) is a plasma membrane-bound transport protein that possesses high capacity to transport mannose (Man) and fructose (Fru) into cells (Grempler et al. 2012). SLC5A10 is exclusively expressed in the kidney and is also able to transport glucose, alpha-methyl-D-glucose (AMG) and galactose, although to a much lower extent than Man and Fru.
Reaction - small molecule participants:
Na+ [cytosol]
Na+ [extracellular region]
Reactome.org reaction link: R-HSA-8876283
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Reaction input - small molecules:
sodium(1+)
Reaction output - small molecules:
sodium(1+)
Reactome.org link: R-HSA-8876283