Reaction: SLC50A1 transports Glc from cytosol to extracellular region
- in pathway: Cellular hexose transport
In mammals, glucose efflux from the liver is crucial for the maintenance of blood glucose levels (Deng & Yan 2016). Human sugar transporter SWEET1 (SLC50A1) is a ubiquitously expressed transport protein, with highest expression in oviduct, epididymis and intestine. It localises to the Golgi membrane where it may supply glucose to the Golgi for secretion from intestinal and liver cells (Chen et al. 2010).
Reaction - small molecule participants:
Glc [extracellular region]
Glc [cytosol]
Reactome.org reaction link: R-HSA-8876319
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Reaction input - small molecules:
alpha-D-glucose
Reaction output - small molecules:
alpha-D-glucose
Reactome.org link: R-HSA-8876319