Reaction: STARD7 binds PC
- in pathway: Synthesis of PC
The steroidogenic acute regulatory (StAR) protein-related lipid transfer (START) domain proteins constitute a family of evolutionarily conserved and widely expressed proteins that have been implicated in lipid transport, metabolism, and signaling. Human StAR-related lipid transfer protein 7 (STARD7, aka GTT1) is a member of the StarD2/phosphatidylcholine transfer protein (PCTP) subfamily that can bind phospholipids and sphingolipids such as phosphatidylcholine (PC). STARD7 is located on the outer mitochondrial membrane and binds ER-membrane PC (Flores-Martin et al. 2013).
Reaction - small molecule participants:
PC [endoplasmic reticulum membrane]
Reactome.org reaction link: R-HSA-8877153
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Reaction input - small molecules:
1,2-diacyl-sn-glycero-3-phosphocholine
Reaction output - small molecules:
Reactome.org link: R-HSA-8877153