Reaction: Synthesis of GABA by GAD2
- in pathway: GABA synthesis
GAD65 or GAD2 is concentrated in the nerve terminal region in the neurons and is involved in the synthesis of GABA which is used as a neurotransmitter.
Reaction - small molecule participants:
GABA [cytosol]
CO2 [cytosol]
L-Glu [cytosol]
H+ [cytosol]
Reactome.org reaction link: R-HSA-888577
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Reaction input - small molecules:
L-glutamate(1-)
hydron
Reaction output - small molecules:
gamma-aminobutyric acid zwitterion
carbon dioxide
Reactome.org link: R-HSA-888577