Reaction: Superoxide and nitric oxide react to peroxynitrite in the phagosome
- in pathway: ROS and RNS production in phagocytes
Inside the phagosome, nitric oxide and superoxide react at diffusion controlled rates with each other to yield peroxynitrite (Prolo C et al. 2014; Ferrer-Sueta G & Radi R 2009).
Reaction - small molecule participants:
Peroxynitrite [phagocytic vesicle lumen]
O2.- [phagocytic vesicle lumen]
NO [phagocytic vesicle lumen]
Reactome.org reaction link: R-HSA-8942052
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Reaction input - small molecules:
superoxide
nitric oxide
Reaction output - small molecules:
peroxynitrite
Reactome.org link: R-HSA-8942052