Reaction: p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18
- in pathway: Receptor Mediated Mitophagy
FUNDC1-mediated mitophagy is inhibited by its phosphorylation at the Tyr 18 position in the LIR motif by Src kinase under normoxia conditions. These phosphorylation events insure that FUNDC1 cannot bind LC3.
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-8948143
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-8948143