Reaction: HDAC4 deacetylates RUNX3
- in pathway: RUNX3 regulates p14-ARF
Histone deacetylase HDAC4, recruited to RUNX3 by CCND1 (cyclin D1), deacetylates RUNX3, leading to BRD2 dissociation (Lee et al. 2013).
Reaction - small molecule participants:
CH3COO- [nucleoplasm]
H2O [nucleoplasm]
Reactome.org reaction link: R-HSA-8952069
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Reaction input - small molecules:
water
Reaction output - small molecules:
acetic acid
Reactome.org link: R-HSA-8952069