Reaction: NAA translocates from mitochondrial matrix to cytosol
- in pathway: Aspartate and asparagine metabolism
Cytosolic acetyl-CoA (Ac-CoA) is used for lipid synthesis in adipocytes. N-acetylaspartate (NAA) is a source of Ac-CoA when catabolised in the cytosol. As no known specific NAA transporters have yet been identified, NAA translocates from the mitochondrial matrix to the cytosol by an unknown mechanism (Prokesch et al. 2016).
Reaction - small molecule participants:
NAA [cytosol]
NAA [mitochondrial matrix]
Reactome.org reaction link: R-HSA-8954513
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Reaction input - small molecules:
N-acetyl-L-aspartic acid
Reaction output - small molecules:
N-acetyl-L-aspartic acid
Reactome.org link: R-HSA-8954513