Reaction: LIPs hydrolyze TG to DAG and LCFA
- in pathway: Digestion of dietary lipid
Lipases are enzymes that hydrolyse dietary lipids such as fats, oils and triglycerides. The majority of human lipases are secreted by the pancreas and function mainly in the digestive system. Humans not only digest fat with pancreatic lipases but also with gastric lipase (LIPF) (Roussel et al. 1999). The pancreatic lipase-related protein 3 (PNLIPRP3) is another candidate lipase included here.
Reaction - small molecule participants:
LCFAs [extracellular region]
DAGs [extracellular region]
H2O [extracellular region]
TAGs [extracellular region]
Reactome.org reaction link: R-HSA-8979996
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Reaction input - small molecules:
water
triglyceride
Reaction output - small molecules:
long-chain fatty acid
diglyceride
Reactome.org link: R-HSA-8979996