Reaction: IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3
- in pathway: Interleukin-20 family signaling
Signal transducer and activator of transcription 3 (STAT3) is phosphorylated after Interleukin-19 (IL19) binds its receptor complex (Dumoutier et al. 2001, Tian et al. 2008, Jain et al.2011). The receptor complex consists of IL19, Interleukin-20 receptor subunit alpha (IL20RA), phosphorylated Tyrosine-protein kinase JAK1 (JAK1), Interleukin-20 receptor beta (IL20RB) and STAT3.
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-8982163
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-8982163