Reaction: IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3
- in pathway: Interleukin-9 signaling
Interleukin-9 receptor (IL9R) is phosphorylated after ligand-receptor interaction. IL9R tyrosine-407 is required for Interleukin-9 (IL9) mediated receptor tyrosine phosphorylation and STAT activation (Demoulin et al. 1996, Bauer et al. 1998).
This is a black box event because it is has not been established which of the JAKs phosphorylates IL9R.
This is a black box event because it is has not been established which of the JAKs phosphorylates IL9R.
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-8985973
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-8985973