Reaction: IL21 receptor JAK phosphorylation
- in pathway: Interleukin-21 signaling
The IL21 heteromeric receptor complex can activate JAK1 and JAK3 in response to Interleukin-21 (IL21), leading to JAK tyrosine phosphorylation (Asao et al. 2001, Habib et al. 2002).
This is a black box event because the mechanism leading to JAK phosphorylation is not established for this receptor complex.
This is a black box event because the mechanism leading to JAK phosphorylation is not established for this receptor complex.
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-9006850
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-9006850