Reaction: kynurenine + pyruvate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + alanine [CCBL2]
- in pathway: Tryptophan catabolism
CCBL2 (KAT 3) catalyzes the reaction of kynurenine and pyruvate to form 4-(2-aminophenyl)-2,4-dioxobutanoate and alanine. CCBL2 is known only as the predicted protein product of a cloned human gene closely homologous to CCBL1 (Yu et al. 2006) and all of the structural and catalytic properties annotated here are inferred from those of CCBL1.
Reaction - small molecule participants:
L-Ala [cytosol]
AP-DOBu [cytosol]
PYR [cytosol]
L-KYN [cytosol]
Reactome.org reaction link: R-HSA-901097
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Reaction input - small molecules:
pyruvate
L-kynurenine
Reaction output - small molecules:
L-alanine zwitterion
4-(2-aminophenyl)-2,4-dioxobutanoic acid
Reactome.org link: R-HSA-901097