Reaction: NTRK2-bound FYN autophosphorylates
- in pathway: Activated NTRK2 signals through FYN
Upon binding to BDNF-activated NTRK2 (TRKB) receptor, autophosphorylation of FYN at tyrosine residue Y420 increases (Mizuno et al. 2003). The exact stoichiometry and involvement of other proteins is not known.
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-9032532
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-9032532