Reaction: NTRK2 phosphorylates CDK5
- in pathway: Activated NTRK2 signals through CDK5
BDNF-activated NTRK2 (TRKB) phosphorylates CDK5 on tyrosine residue Y15, thus increasing CDK5 catalytic activity (Cheung et al. 2007).
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-9032854
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-9032854