Reaction: NTRK2 promotes TIAM1 phosphorylation
- in pathway: Activated NTRK2 signals through CDK5
Upon binding to NTRK2 (TRKB), TIAM1 is phosphorylated at tyrosine residue Y829, presumably by NTRK2, but this has not been shown directly (Lai et al. 2012).
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-9033284
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-9033284