Reaction: TYSND1 cleaves ACAA1
- in pathway: TYSND1 cleaves peroxisomal proteins
The trypsin-like serine-type endopeptidase TYSND1 cleaves ACAA1 between amino acid residues 26 and 27, yielding ACAA1(1-26) and ACAA1(27-424) (Okumoto et al. 2011). In mice, knockout of Tysnd1 causes reduced localization of Acaa1 to the peroxisome.
Reaction - small molecule participants:
H2O [peroxisomal matrix]
Reactome.org reaction link: R-HSA-9033529
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Reaction input - small molecules:
water
Reaction output - small molecules:
Reactome.org link: R-HSA-9033529