Reaction: SRC,FYN phosphorylate NTRK2
- in pathway: Activated NTRK2 signals through FYN
Activated SRC and, probably FYN, can phosphorylate NTRK2 (TRKB) on tyrosine residues Y706 and Y707 in the absence of ligand binding, thus increasing the catalytic activity of NTRK2 (Huang and McNamara 2010).
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-9037040
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-9037040