Reaction: beta-alanine + pyruvate => 3-oxopropanoate + alanine
- in pathway: Pyrimidine catabolism
Mitochondrial AGXT2 tetramer catalyzes the reaction of beta-alanine and pyruvate to form 3-oxopropanoate and alanine. While the human mitochondrial AGXT2 enzyme has been characterized experimentally in other respects (Rodionov et al. 2010), its ability to catalyze this transamination reaction is inferred from the properties of its rat homologue.
Reaction - small molecule participants:
OPROP [mitochondrial matrix]
L-Ala [mitochondrial matrix]
b-Ala [mitochondrial matrix]
PYR [mitochondrial matrix]
Reactome.org reaction link: R-HSA-909776
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Reaction input - small molecules:
beta-alanine zwitterion
pyruvate
Reaction output - small molecules:
3-oxopropanoate
L-alanine zwitterion
Reactome.org link: R-HSA-909776