Reaction: Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein
- in pathway: O-linked glycosylation of mucins
An unknown N-acetylglucosaminyltransferase mediates the transfer of GlcNAc to Tn antigens via an alpha-1,3 linkage to create Core 5 mucins (Brockhausen et al. 2009).
Reaction - small molecule participants:
UDP [Golgi lumen]
UDP-GlcNAc [Golgi lumen]
Reactome.org reaction link: R-HSA-914005
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Reaction input - small molecules:
UDP-N-acetyl-alpha-D-glucosamine(2-)
Reaction output - small molecules:
UDP(3-)
Reactome.org link: R-HSA-914005