Reaction: Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein
- in pathway: O-linked glycosylation of mucins
An unknown galactosyltransferase mediates the transfer of galactose is transferred to Tn antigens via an alpha-1,3 linkage to create Core 8 mucins (Brockhausen et al. 2009).
Reaction - small molecule participants:
UDP [Golgi lumen]
UDP-Gal [Golgi lumen]
Reactome.org reaction link: R-HSA-914006
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Reaction input - small molecules:
UDP-alpha-D-galactose(2-)
Reaction output - small molecules:
UDP(3-)
Reactome.org link: R-HSA-914006