Reaction: Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein
- in pathway: O-linked glycosylation of mucins
An unknown N-acetylgalactosaminyltransferase mediates the transfer of GalNAc is transferred to Tn antigens via an alpha-1,6 linkage to create Core 7 mucins (Brockhausen et al. 2009).
Reaction - small molecule participants:
UDP [Golgi lumen]
UDP-GalNAc [Golgi lumen]
Reactome.org reaction link: R-HSA-914017
======
Reaction input - small molecules:
UDP-N-acetyl-D-galactosamine(2-)
Reaction output - small molecules:
UDP(3-)
Reactome.org link: R-HSA-914017