Reaction: apoTF binds 2Fe3+ to form holoTF
- in pathway: Iron uptake and transport
Transferrin (TF) is the main transporter of iron in the blood. The apo-form of TF can take up two ferric iron ions (Fe3+) to form holoTF (Wally et al. 2006).
Reaction - small molecule participants:
Fe3+ [extracellular region]
Reactome.org reaction link: R-HSA-917888
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Reaction input - small molecules:
iron(3+)
Reaction output - small molecules:
Reactome.org link: R-HSA-917888