Reaction: Sulfhydrylation and ring cleavage of precursor Z
- in pathway: Molybdenum cofactor biosynthesis
After the MOCS2A dimer is loaded with two sulfur atoms, their sequential deposition on the precursor Z molecule, with ring cleavage, is catalyzed by the MOCS2B half of the MOCS2 tetramer (Leimkuhler et al, 2003; Wuebbens & Rajagopalan, 2002).
Reaction - small molecule participants:
H+ [cytosol]
MPT [cytosol]
Precursor Z [cytosol]
H2O [cytosol]
Reactome.org reaction link: R-HSA-947541
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Reaction input - small molecules:
precursor Z(1-)
water
Reaction output - small molecules:
hydron
molybdopterin(3-)
Reactome.org link: R-HSA-947541