Reaction: Endocytic Uptake of HCMV Virion
- in pathway: HCMV Early Events
Once the pentameric viral protein complex, gH:gL:p128:p130:p131A, facilitates attchment of the Human Cytomegalovirus (HCMV) endocytic uptake allows the virion to enter epithelial and endothelial cells. The virion is released from the endocytic vesicle by low-pH-dependent fusion of the virion coat with endosomes membrane.
Reaction - small molecule participants:
HSPG [plasma membrane]
Reactome.org reaction link: R-HSA-9611147
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Reaction input - small molecules:
Reaction output - small molecules:
heparan sulfate proteoglycan
Reactome.org link: R-HSA-9611147