Reaction: All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene
- in pathway: Transcriptional regulation of granulopoiesis
The RARA:RXR heterodimeric retinoic acid receptor binds a retinoic acid receptor element (RARE) in the promoter of the CEBPE gene (Park et al. 1999). Retinoic acid binds RARA:RXR at the CEBPE gene and activates transcription of CEBPE (Park et al. 1999).
Reaction - small molecule participants:
atRA [nucleoplasm]
Reactome.org reaction link: R-HSA-9617067
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Reaction input - small molecules:
all-trans-retinoic acid
Reaction output - small molecules:
Reactome.org link: R-HSA-9617067