Reaction: PPM1F dephosphorylates p-T286-CaMKII

- in pathway: Negative regulation of NMDA receptor-mediated neuronal transmission
Protein phosphatase 1F (PPM1F, also known as CaM-kinase phosphatase or CaMKPase) dephosphorylates the autophosphorylated threonine residue of CaMKII (CAMK2), thus inactivating CaMKII kinase activity (Ishida et al. 1998).
Reaction - small molecule participants:
Pi [cytosol]
H2O [cytosol]
Reactome.org reaction link: R-HSA-9619449

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Reaction input - small molecules:
water
ChEBI:15377
Reaction output - small molecules:
hydrogenphosphate
ChEBI:43474
Reactome.org link: R-HSA-9619449