Reaction: CAMK1 phosphorylates ARHGEF7-1
- in pathway: Activation of RAC1 downstream of NMDARs
At dendritic spines, CAMK1, activated by CaMKK-mediated phosphorylation downstream of NMDA receptor activation, phosphorylates GIT1-bound ARHGEF7 (beta-PIX) on serine residue S516 (Saneyoshi et al. 2013).
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-9619783
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-9619783