Reaction: PGM1:Mg2+ isomerises G1P to G6P
- in pathway: Galactose catabolism
Cytosolic phosphoglucomutase 1 (PGM1) catalyzes the reversible conversion of glucose 1-phosphate to glucose 6-phosphate. Two PGM isoenzymes, both monomers, have been identified. PGM1 is the major form found in most tissues except erythrocytes, where PGM2 is abundant (March et al. 1993; Quick et al. 1974).
Reaction - small molecule participants:
G6P [cytosol]
G1P [cytosol]
G6P [cytosol]
G1P [cytosol]
Reactome.org reaction link: R-HSA-9638125
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Reaction input - small molecules:
D-glucopyranose 1-phosphate(2-)
D-glucopyranose 1-phosphate(2-)
Reaction output - small molecules:
alpha-D-glucose 6-phosphate(2-)
alpha-D-glucose 6-phosphate(2-)
Reactome.org link: R-HSA-9638125