Reaction: 2xPNPO:2xFMN oxidizes PXAP to PXLP
- in pathway: Vitamin B6 activation to pyridoxal phosphate
Pyridoxine-5'-phosphate oxidase (PNPO) is able to oxidize pyridoxamine phosphate (PXAP) to pyridoxal 5'-phosphate (PXLP) (Kang et al. 2004).
Reaction - small molecule participants:
PXLP [cytosol]
NH4+ [cytosol]
H2O2 [cytosol]
H2O [cytosol]
O2 [cytosol]
PXAP [cytosol]
Reactome.org reaction link: R-HSA-965079
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Reaction input - small molecules:
water
dioxygen
pyridoxamine 5'-phosphate
Reaction output - small molecules:
pyridoxal 5'-phosphate(2-)
ammonium
hydrogen peroxide
Reactome.org link: R-HSA-965079