Reaction: ADORA2B:Ade-Rib:GsGTP dissociates
- in pathway: ADORA2B mediated anti-inflammatory cytokines production
The classical view of G-protein signalling is that the G-protein alpha subunit dissociates from the beta:gamma dimer. Activated G alpha (s) and the beta:gamma dimer then participate in separate signaling cascades. Although G protein dissociation has been contested (e.g. Bassi et al. 1996), recent in vivo experiments have demonstrated that dissociation does occur, though possibly not to completion (Lambert 2008).
Reaction - small molecule participants:
Ade-Rib [extracellular region]
Reactome.org reaction link: R-HSA-9660819
======
Reaction input - small molecules:
Reaction output - small molecules:
adenosine
Reactome.org link: R-HSA-9660819